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Antiage, the fillers become super tech: the “liquid threads” give the lifting effect

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Solve the problem of collagen loss? Yes, that’s possible. Gouri, dermal injectable, is the new innovative skin collagen stimulator for facial rejuvenation and lifting. Its peculiarity: «It has a completely liquid form – he explains Marco Bartolucci, aesthetic physician and founder of the Sotherga and KOL clinics and Gouri’s injector trainer — unlike other polymer-based injectables’. It cannot be considered a filler. “It spreads evenly under the skin, forming a supportive matrix that stimulates fibroblasts. It promotes neocollagenesis and restores levels lost during the aging process.” Gouri is polycaprolactone (PCL) with an exclusive technology that makes it soluble. «I call them liquid threads – says Bartolucci -. The amount of collagen produced is such that the laxity of the treated area is improved (lifting effect). It’s the Gouri touch».


Gouri’s characteristics compensate for the limitations of existing products. Dermal fillers currently used fill wrinkles or add volume to a localized area. But they are not suitable for improving all skin qualities. Gouri does not give instant volume or an anti-wrinkle effect, but it can restore collagen synthesis with temporary volume improvements. There are some products that need to be injected all over the face to get the collagen effect. However, this practice leads to a lot of pain and discomfort, also caused by the microparticles in the existing fillers.

The improvement of wrinkles and elasticity

Appreciation of improvement of wrinkles increased by up to 48%. Independent evaluators and testers rated the CFGS (this is the “crow’s feet” rating scale) for each application area of ​​Gouri and a competitor at two weeks, four weeks, and 12 weeks after the last application. The “liquid threads” showed greater improvement on both a resting face and a smiling face. Also immediate dermal elevation after treatment.

What is PCL?

«Skin has a basic need: deep hydration is a fundamental key to anti-aging. It ensures constant and sufficient collagen synthesis to obtain a truly youthful skin, prevents the appearance of wrinkles and improves the level of other aging indicators,” explains Marco Bartolucci. «PCL is a synthetically developed biocompatible polymer that is biodegradable and bioresorbable, which belongs to the same chemical family as poly-L-lactic acid (PLLA) and polyglycolic acid (PGA). As a non-toxic, non-allergenic and bioresorbable material, PCL has a wide range of applications such as controlled release drug delivery, tissue engineering systems (3D scaffolds/matrixes), absorbable sutures and many more. This diversity of applications is possible due to its better viscoelastic properties compared to other polymers, allowing the skilled person to easily manipulate the structure. In aesthetics, PCL is used as a collagen stimulator and has so far been shown in the form of skin threads and injectables, which consist of microspheres. Gouri’s PCL, while maintaining this great advantage, takes the capabilities of polycaprolactone even further thanks to an exclusive CESABP (Collagenese-Enabled Active Solubilized and Biodegradable Polymer) technology, which makes the PCL completely soluble. The complete dissolution of the polycaprolactone allows the injector to remove particles that can cause side effects such as overcorrection, nodules or even occlusions».

Source: Corriere

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