According to a prospective controlled open-label study, a saline-based nasal spray could reduce Pap smear positivity by 2 days. The research was carried out by Luca Cegolon from the University of Trieste and by Giuseppe Mastrangelo from the University of Padua
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According to an open-label controlled prospective study conducted by Luca Cegolon of the University of Trieste and Giuseppe Mastrangelo of the University of Padua, a saline-based nasal spray could reduce smear positivity by 2 days to reveal Sars-CoV – 2, compared to patients treated with standard therapy. This, dubbed ‘Trial Clinico Renaissance’ (Regressed Nasal Infectivity and Shedding of SARS-CoV-2 by Achieving Negativization for COVID-19 Earlier), was conducted with the support of the ENT Department of Ca’ Foncello Hospital in Treviso.
What the study says
According to what emerged from the research, the component responsible for the antiviral effect appears to be sea water, already famous for its great antiviral and antimicrobial properties. Based on the assumption that the main route of entry of the virus into the human body is the nose, and with it the other respiratory tracts such as the throat and bronchi, the research has focused precisely on this aspect to investigate the role of seawater. Indeed, this would stimulate the glands of the nasal mucosa to produce hypochlorous acid (HClO), thereby reducing the effect of the virus.
The data
To prove the study, 108 patients affected by Covid-19 were involved: these, recruited from the Covid-19 point of Treviso between February and March 2022, so during the Omicron wave, were then divided into two groups. One of 50 will receive standard Covid-19 therapy and a saline-based nasal spray, and one of 58 will receive standard Covid-19 therapy only. The first group received the saline solution 3 times a day, then once every eight hours: this showed that in the first five days of treatment, patients treated with nasal saline solution became negative an average of 2 days before the controls.
Covid in Italy
In Italy, according to the new independent monitoring of the Gimbe Foundation, referring to the week between November 25 and December 1, an increase was recorded in ordinary hospital admissions with positive reactions to the Sars-CoV-2 coronavirus (+11.1%) and intensive care hospitalizations (+28%), compared to the previous week. However, while the new cases of Covid-19 remain almost stable (227,420 against 229,122 in the previous week), the number of deaths rises from 580 to 635, ie 55 more, of which 14 relate to previous periods (+9.5%).
Source: TG 24 Sky
I am Barbara Redford, a professional journalist and writer with extensive experience in news reporting. I have been writing for The News Dept since 2019, covering topics related to health and wellness. My passion is to keep people informed about the latest developments in healthcare and the medical industry. With my articles, I strive to create awareness on various diseases while also highlighting their remedies or treatments.
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